Venkatakrishna R Jala Selected Research

Leukotriene B4

1/2018	Mast Cell-Dependent CD8+ T-cell Recruitment Mediates Immune Surveillance of Intestinal Tumors in ApcMin/+ Mice.
1/2018	Inflammasome-Independent Leukotriene B4 Production Drives Crystalline Silica-Induced Sterile Inflammation.
10/2017	The yin and yang of leukotriene B4 mediated inflammation in cancer.
1/2017	Leukotriene B4-receptor-1 mediated host response shapes gut microbiota and controls colon tumor progression.
4/2015	Crystalline silica-induced leukotriene B4-dependent inflammation promotes lung tumour growth.
9/2010	Nonredundant roles for leukotriene B4 receptors BLT1 and BLT2 in inflammatory arthritis.
11/2007	Role of leukotriene B4 receptors in rheumatoid arthritis.
3/2007	Critical role for polar residues in coupling leukotriene B4 binding to signal transduction in BLT1.
2/2005	Phosphorylation-independent beta-arrestin translocation and internalization of leukotriene B4 receptors.
2/2004	Role of leukotriene B4 receptors in the development of atherosclerosis: potential mechanisms.

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Venkatakrishna R Jala Research Topics

Disease

14	Inflammation (Inflammations) 01/2022 - 09/2006
8	Neoplasms (Cancer) 01/2019 - 03/2007
5	Atherosclerosis 01/2017 - 02/2004
4	Arthritis (Polyarthritis) 01/2017 - 03/2007
3	Asthma (Bronchial Asthma) 01/2017 - 03/2007
2	Colitis 01/2022 - 01/2022
2	Silicosis 01/2018 - 04/2015
2	Lung Neoplasms (Lung Cancer) 01/2018 - 04/2015
2	Infections 10/2017 - 12/2007
2	Neoplasm Metastasis (Metastasis) 10/2017 - 03/2016
2	Leukemia 02/2005 - 02/2004
1	Ulcerative Colitis 01/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019
1	Fatty Liver 10/2018
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2018
1	Hypersensitivity (Allergy) 10/2017
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2016
1	Experimental Melanoma 01/2016
1	Fibrosis (Cirrhosis) 01/2016
1	Colorectal Neoplasms (Colorectal Cancer) 03/2015
1	Waterborne Diseases 01/2014
1	Diarrhea 01/2014
1	Malnutrition (Nutritional Deficiencies) 01/2014
1	Cryptosporidiosis 01/2014
1	Body Weight (Weight, Body) 01/2014
1	Ovarian Neoplasms (Ovarian Cancer) 07/2012
1	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2011
1	Hyperplasia 10/2011
1	Disease Progression 10/2011
1	Obesity 08/2011
1	Insulin Resistance 08/2011
1	Wounds and Injuries (Trauma) 06/2009
1	Peritonitis 12/2007
1	Rheumatoid Arthritis 11/2007

Drug/Important Bio-Agent (IBA)

10	Leukotriene B4IBA 01/2018 - 02/2004
7	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 01/2018 - 02/2004
3	ChemokinesIBA 01/2018 - 02/2004
3	LeukotrienesIBA 01/2017 - 06/2004
3	Chemotactic FactorsIBA 01/2016 - 02/2004
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2009
2	Anti-Bacterial Agents (Antibiotics)IBA 10/2018 - 01/2017
2	Silicon Dioxide (Silica)FDA LinkGeneric 01/2018 - 04/2015
1	Dextran SulfateIBA 01/2022
1	Toll-Like Receptor 4IBA 01/2022
1	Dextrans (Dextran)FDA Link 01/2022
1	Hyaluronic Acid (Hyaluronan)IBA 01/2022
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2022
1	Pharmaceutical PreparationsIBA 01/2022
1	SuspensionsIBA 01/2022
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2022
1	Immunomodulating AgentsIBA 01/2022
1	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 01/2019
1	3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-oneIBA 01/2019
1	Gemcitabine FDA Link 01/2019
1	InflammasomesIBA 01/2018
1	4- (2,3- dihydro- 1,4- benzodioxin- 6- yl)- 2,4- dihydro- 5- ((5- nitro- 2- thiazolyl)thio)- 3H- 1,2,4- triazol- 3- oneIBA 01/2018
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2017
1	RNA (Ribonucleic Acid)IBA 03/2016
1	Tight Junction ProteinsIBA 03/2016
1	IronIBA 01/2016
1	Blood Glucose (Blood Sugar)IBA 01/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016
1	VaccinesIBA 01/2016
1	EnzymesIBA 01/2016
1	sipuleucel-T (APC8015)FDA Link 04/2015
1	IpilimumabIBA 04/2015
1	pembrolizumabIBA 04/2015
1	Volatile Fatty AcidsIBA 03/2015
1	IMP DehydrogenaseIBA 01/2014
1	Biological Warfare AgentsIBA 01/2014
1	Paromomycin (Paromomycin Sulfate)FDA LinkGeneric 01/2014
1	Interleukin-12 (IL 12)IBA 01/2014
1	Therapeutic UsesIBA 07/2012
1	Cisplatin (Platino)FDA LinkGeneric 07/2012
1	withaferin AIBA 07/2012
1	Interleukin-23 (Interleukin 23)IBA 10/2011
1	Interleukin-17 ReceptorsIBA 10/2011
1	Interleukin-17 (Interleukin 17)IBA 10/2011
1	Triglycerides (Triacylglycerol)IBA 08/2011
1	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 08/2011
1	Glucose (Dextrose)FDA LinkGeneric 08/2011
1	Insulin (Novolin)FDA Link 08/2011
1	LipidsIBA 09/2010
1	AutoantibodiesIBA 09/2010
1	Transforming Growth Factors (Transforming Growth Factor)IBA 06/2009
1	Transforming Growth Factor beta (TGF-beta)IBA 06/2009
1	activin AIBA 06/2009
1	LigandsIBA 08/2008
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2007
1	Interleukin-10 (Interleukin 10)IBA 12/2007
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 03/2007
1	Cell Surface ReceptorsIBA 09/2006
1	Platelet Activating FactorIBA 09/2006
1	ApolipoproteinsIBA 02/2004

Therapy/Procedure

4	Therapeutics 01/2022 - 09/2010
3	Immunotherapy 10/2017 - 04/2015
1	Enema (Enemas) 01/2022
1	Drug Therapy (Chemotherapy) 10/2017
1	Fecal Microbiota Transplantation 01/2017